xenobiology

Directed Evolution

My work at UCL on directed evolution methods, using bacterial surface display for xenobiology.

Bacterial cell display as a robust and versatile platform for the engineering of low affinity ligands and enzymes

Directed evolution has been remarkably successful at expanding the chemical and functional boundaries of biology. That progress is heavily dependent on the robustness and flexibility of the available selection platforms, given the significant cost to …

Synthetic biology approaches to biological containment- pre-emptively tackling potential risks

Biocontainment comprises any strategy applied to ensure that harmful organisms are con- fined to controlled laboratory conditions and not allowed to escape into the environment. Genetically engineered microorganisms (GEMs), regardless of the nature …